Describe a particular challenge in the conduct of a randomized trial and present either their solution to this or the approach that they would take to reach a solution.
Describe a particular challenge in the conduct of a randomized trial and present either their solution to this or the approach that they would take to reach a solution.
Learning objectives
to identify whether it would be beneficial to have a pilot trial before your main trial
to identify a SWAT (Study Within A Trial) that might be done within your trial
to identify any issues that have not been resolved
to identify how to resolve outstanding issues about your trial As you
are resubmitting the assignment, you must follow the original assignment
instructions but you must base your assignment on two new challenges or
issues. You must not re-use any part of your original assignment
submission.
describe a particular challenge in the conduct of a randomised trial
and present either their solution to this or the approach that they
would take to reach a solution. If one or
both of the assignments can take the form of the outline for a SWAT
(Study Within A Trial) in which the particular challenge and a possible
solution to it would be presented using the SWAT template with
information on the background to the SWAT,
its objective,
the area of the trial to be investigated,
any interventions or actions that would be compared (and the method for
allocating to different interventions or actions), the outcome measures
to determine the effects of the interventions or actions and how these
would be analysed, and any possible problems in implementing this SWAT.